The Broad Institute, Inc.;Massachusetts Institute of Technology
发明人:
Feng Zhang
申请号：
US14256912
公开号：
US08945839B2
申请日:
2014.04.18
申请国别(地区):
US
年份:
2015
代理人:
摘要：
The invention provides for systems, methods, and compositions for altering expression of target gene sequences and related gene products. Provided are vectors and vector systems, some of which encode one or more components of a CRISPR complex, as well as methods for the design and use of such vectors. Also provided are methods of directing CRISPR complex formation in eukaryotic cells and methods for utilizing the CRISPR-Cas system.
