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Vectors
专利权人:
Autolus Limited
发明人:
THOMAS, Simon,ONUOHA, Shimobi,CORDOBA, Shaun
申请号:
AU2018361810
公开号:
AU2018361810A1
申请日:
2018.10.31
申请国别(地区):
AU
年份:
2020
代理人:
摘要:
The present invention provides a kit of vectors comprising: (i) a first vector comprising a nucleic acid sequence encoding a first marker component; and (ii) a second vector comprising a nucleic acid sequence encoding a second marker component, wherein, when a cell is transduced with both the first and second vectors, the first and second marker components are expressed by the cell and associate forming a hetero- multimeric marker which is recognised by a cell sorting reagent whereas, when a cell is transduced with either the first or second vector alone, expression of the first or second marker component alone is not recognised by the cell sorting reagent.
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