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Système d'administration de médicament contrôlée par rétention gastrique
专利权人:
SUN PHARMA ADVANCED RESEARCH COMPANY LTD
发明人:
申请号:
EP10165807.8
公开号:
EP2238975B1
申请日:
2002.07.04
申请国别(地区):
EP
年份:
2012
代理人:
摘要:
The present invention provides a gastric retention controlled drug delivery system comprising: (a) a controlled release core comprising a drug, a highly swellable polymer and a gas generating agent, said core being capable of swelling and achieving floatation rapidly while maintaining its physical integrity in gastrointestinal fluids for prolonged periods, and (b) a rapidly releasing coat composition comprising the same drug as in the core and pharmaceutically acceptable excipients, wherein the coating composition surrounds the core such that the system provides a biphasic release of the drug in gastrointestinal fluids.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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