INHIBITEURS DU FACTEUR MACROCYCLIQUE VIIA UTILES EN TANT QU ANTICOAGULANTS

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专利权人:

BRISTOL-MYERS SQUIBB COMPANY

发明人:

申请号：

EP06846746.3

公开号：

EP1971582B1

申请日:

2006.12.21

申请国别(地区):

EP

年份:

2012

代理人:

摘要：

The present invention relates generally to novel macrocycles of Formula (I): or stereoisomers, tautomers, pharmaceutically acceptable salts, solvates, or prodrugs thereof, wherein the variables A, B, L, M, W, Z, R1, R2, R3, R4, R5, R6, R7, R8, R9, and R10 are as defined herein. These compounds are selective inhibitors of the serine protease coagulation factor VIIa which can be used as medicaments.

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