The present invention is an esophageal stethoscope with a temperature sensor and earpiece. An esophageal stethoscope has a tube with a first end and a second end, where a sound-transmitting hydrophobic cuff covers the first end of the tube. The first end of the tube has a plurality of lateral openings and a thermistor extending from the first end but within the cuff. The second end of the tube is attached to a connector and has a temperature sensor sub-assembly that extends out of the second end and is connected to the thermistor. A monoscope tube is attached to the connector at a first end and has a memory foam earpiece at a second end. The monoscope tube also preferably has a clip near the earpiece. To facilitate sound transmission, monoscope tubes of different ID sizes are used.