The present invention aims to provide an adsorption carrier-packed column which enables reduction of bypassing, and improvement of the performance of the adsorption carrier. The present invention provides an adsorption carrier-packed column comprising a central pipe, adsorption carrier, plate A, and plate B, wherein an insertion material C is inserted between the adsorption carrier and the plate A an insertion material D is inserted between the adsorption carrier and the plate B the ratio of the deformation rate of the insertion material C (C 1 ) to the deformation rate of the adsorption carrier (E 0 ) is 1‰¤C 1 /E 0 ‰¤10, and the ratio of the deformation rate of the insertion material D (D 1 ) to the deformation rate of the adsorption carrier (E 0 ) is 1‰¤D 1 /E 0 ‰¤10 and the ratio of the thickness of the insertion material C (T C ) to the distance of a gap between the adsorption carrier and the plate A (L A ) is 1.1‰¤T C /L A ‰¤4, and the ratio of the thickness of the insertion material D (T D ) to the distance of a gap between the adsorption carrier and the plate B (L B ) is 1.1‰¤T D /L B ‰¤4.