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Pharmaceutical composition for oral administration
专利权人:
ASTELLAS PHARMA INC.
发明人:
Seiji Takae,Hiroyuki Kojima,Atsushi Sakurai,Tetsuya Tamura,Hiroaki Tasaki,Atsushi Muro
申请号:
US14779328
公开号:
US09408835B2
申请日:
2014.03.28
申请国别(地区):
US
年份:
2016
代理人:
摘要:
A pharmaceutical composition containing, as the active ingredient, 4-{[(1R,2s,3S,5s,7s)-5-hydroxy-2-adamantyl]amino}-1H-pyrrolo[2,3-b]pyridine-5-carboxamide, of which the solubility in an acidic pH region is different from that in a neutral pH region, with rapid disintegration property and rapid drug dissolution property as well as the expectation of a good drug dosing compliance, is provided. The pharmaceutical composition for oral administration of the present invention contains 4-{[(1R,2s,3S,5s,7s)-5-hydroxy-2-adamantyl]amino}-1H-pyrrolo[2,3-b]pyridine-5-carboxamide or a pharmaceutically acceptable salt thereof, and a hydrophilic lubricant, and is useful as a pharmaceutical composition for oral administration with rapid disintegration property and rapid drug dissolution property as well as the expectation of a good drug dosing compliance.
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中国工程科技知识中心
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