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PERFORMANCE PERFORMANCE AND TRANSDERMAL DRUG WITH ITS USE
专利权人:
ТОА ЭЙО ЛТД. (JP)
发明人:
ОХТАКЕ Наото (JP),КОИДЕ Юуки (JP)
申请号:
RU2011102454/15
公开号:
RU2011102454A
申请日:
2009.06.22
申请国别(地区):
RU
年份:
2012
代理人:
摘要:
1. The percutaneous absorption enhancer containing sulfosuccinate or its salt and an alkyl glycoside or alkylthioglycoside. ! 2. The transdermal absorption enhancer according to claim 1, wherein the transdermal absorption enhancer is contained in a matrix type transdermal preparation. ! 3. The transdermal absorption enhancer according to claim 1 or 2, wherein the sulfosuccinate or its salt is C6-C18 dialkyl sulfosuccinate or its salt. ! 4. The transdermal absorption enhancer of claim 1 or 2, wherein the alkyl glycoside or alkylthioglycoside is a C6-C18 alkyl glycoside or a C6-C18 alkylthioglycoside. ! 5. The transdermal absorption enhancer according to claim 1 or 2, wherein the sulfosuccinate or its salt is dioctyl sulfosuccinate or a salt of dioctyl sulfosuccinate. ! 6. The transdermal absorption enhancer according to claim 1 or 2, wherein the alkyl glycoside or alkylthioglycoside is n-octyl-β-D-thioglucopyranoside or n-dodecyl-β-D-glucopyranoside. ! 7. A transdermal matrix-type preparation containing:! a percutaneous absorption enhancer according to any one of claims 1 to 6, and a drug. ! 8. The transdermal preparation of the matrix type according to claim 7, wherein the transdermal preparation of the matrix type is a preparation on an adhesive tape. ! 9. The matrix type transdermal preparation according to claim 7 or 8, in which each of the drug-containing layers containing the matrix material, the drug and the transdermal absorption enhancer according to any one of claims 1 to 6 are layered on one surface of the substrate sheet. ! 10. The matrix type transdermal preparation according to claim 9, in which the matrix material consists of an acrylic adhesive base based on adhesive rubber1. Усилитель чрескожного всасывания, содержащий сульфосукцинат или его соль и алкилгликозид или алкилтиогликозид. ! 2. Усилитель чрескожного всасывания по п.1, при этом усилитель чрескожного всасывания содержится в трансдермальном препарате матричного типа. ! 3. Усилитель чрескожн
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