Synthèse d'épitholones, intermédiaires, analogues et leur utilisation

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专利权人:

SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH

发明人:

申请号：

EP03022736.7

公开号：

EP1386922B1

申请日:

1997.12.03

申请国别(地区):

EP

年份:

2012

代理人:

摘要：

The present invention provides convergent processes for preparing epothilone A and B, desoxyepothilones A and B, and analogues thereof. Also provided are analogues related to epothilone A and B and intermediates useful for preparing same. The present invention further provides novel compositions based on analogues of the epothilones and methods for the treatment of cancer and cancer which has developed a multidrug-resistant phenotype.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/