Peter Bertinato;Ting-Chao Chou;Dai-shi Su;Aaron Balog;Samuel J. Danishefsky;Ted Kamenecka;Kenneth A. Savin;Dongfang Meng;Erik J. Sorensen
发明人:
Samuel J. Danishefsky,Peter Bertinato,Dai-shi Su,Dongfang Meng,Ting-Chao Chou,Ted Kamenecka,Erik J. Sorensen,Aaron Balog,Kenneth A. Savin
申请号：
US13040211
公开号：
US08481575B2
申请日:
2011.03.03
申请国别(地区):
US
年份:
2013
代理人:
摘要：
The present invention provides convergent processes for preparing epothilone A and B, desoxyepothilones A and B, and analogues thereof. Also provided are analogues related to epothilone A and B and intermediates useful for preparing same. The present invention further provides novel compositions based on analogues of the epothilones and methods for the treatment of cancer and cancer which has developed a multidrug-resistant phenotype.
