Peder Oscar Andersen,Olav Gåseröd,Christian Klein Larsen
申请号：
US13089972
公开号：
US09017720B2
申请日:
2011.04.19
申请国别(地区):
US
年份:
2015
代理人:
摘要：
The present invention is directed to seamless capsules and methods for making seamless capsules having a high oil content as described herein. More specifically, the present invention is directed to seamless capsules, and methods for making seamless capsules, made from a process involving the steps of: (a) preparing an emulsion comprising oil, water, an emulsifier, and at least one of a water-soluble monovalent metal salt, polyvalent metal salt, and an acid, wherein said oil is present in an amount of at least 50% by weight of said emulsion with the proviso that said emulsion does not contain marmelo mucilage and (b) adding portions of said emulsion to an aqueous gelling bath comprised of at least one ionic polysaccharide thereby encapsulating said portions of said emulsion in a polysaccharide gel membrane, and optionally (c) drying the resulting capsules by removing water.Improved methods are described for preparing seamless capsules comprising oil and water emulsions containing high concentrations of oil, where the emulsions are suitable for encapsulation into capsules of a polysaccharide gel. Of particular interest are emulsions of oil and water, where the oil is present in an amount of at least 50% by weight of the emulsion and the capsule is, for example, an alginate gel. Oils that are a pharmaceutical active agent, a nutritional supplement or a food or oils that act as a carrier therefore, are also of particular interest. According to a preferred embodiment of the present invention the emulsion may contain further solid or liquid or gaseous components and be mixed to a dispersion before the encapsulation. The capsules of the invention are suitable for a variety of applications, e.g., pharmaceutical, nutraceutical, veterinary, agricultural, cosmetic, or food applications.
