A control unit attachable to a flexible endoscope having a shaft deflectable via two rotatable knobs is provided. The control unit includes a user interface including a first interface being mounted on a pivotal support attached to a housing of the control unit, the first interface being engageable by a palm of a hand. The control unit further includes a drive unit operable via the user interface, the drive unit including a first drive mechanism for engaging the two rotatable knobs thereby allowing a user to control deflection of the shaft of the endoscope via the first interface.
