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NOUVEAU GROUPE DE PEPTIDES POUR TRAITER LES TROUBLES SEXUELS CHEZ LA FEMME
专利权人:
Company Limited "Ivix"
发明人:
申请号:
EP17866053.6
公开号:
EP3530666A1
申请日:
2017.10.02
申请国别(地区):
EP
年份:
2019
代理人:
摘要:
The invention relates to the chemistry of peptides, pharmacology and medicine, and specifically to a new group of peptides having the property of stimulating sexual and genital function and having increased storage stability. For this purpose, peptides of general formula (I) are proposed: A-Thr-Lys-Hyp -B-C-D-X, in which A is 0, Met, Met(0), Thr, Ala, His, Phe, Lys, Gly; B is 0, Gly, Asp, Trp, Gin, Asn, Tyr, Hyp, Arg; C is 0, Arg, Phe, Tyr, Gly, His, Hyp, Lys; D is 0, Val, Gly, Tyr, Trp, Phe, His; X is OH, OCH3, NH2; where 0 is the absence of an amino acid residue, provided that if A ≠ 0, then B and/or C and/or D ≠ 0, if B ≠ 0, then C and/or D ≠ 0, excluding the tetrapeptides, as well as the peptides Phe-Thr-Lys-Hyp-Gly, Thr-Lys-Hyp-Hyp-Arg and Thr-Lys-Hyp-Arg-Gly. The invention also relates to pharmaceutical compositions containing the indicated peptides, as well as to the use of the above indicated compositions for the treatment of women with severely decreased libido or with totally absent libido, orgasmic dysfunction, sexual dysfunction not caused by organic disorders or diseases, HSDD, FSAD or FSIAD, and to a method of treating and/or preventing female sexual dysfunction.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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