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VERFAHREN ZUR HERSTELLUNG VON GRANULEN ENTHALTEND EINEN AKTIVEN VERBINDUNG, MIT VERBESSERTEN STABILITÄT UND GEHALT AN AKTIVEN
专利权人:
Expressions Aromatiques
发明人:
CARPENTIER, Vincent,RAVEL, Bénédicte
申请号:
EP14738568.6
公开号:
EP3019028B1
申请日:
2014.06.20
申请国别(地区):
EP
年份:
2019
代理人:
摘要:
A method for producing granules that contain at least one active ingredient and are stable at ambient temperature, includes successively: (1) preparing a matrix free of an active ingredient by mixing, without the addition of water, an encapsulation vehicle for the active ingredient and a non-aqueous plasticiser compatible with the vehicle and the active ingredient, the encapsulation vehicle and the plasticiser being present in amounts that give the matrix a glass transition temperature higher than the ambient temperature; (2) heating the matrix in an extruder to an extrusion temperature to produce an amorphous melt matrix; (3) injecting the active ingredient into the melt matrix; (4) extruding the melt mass including the active ingredient through a die and cutting granules at an exit point of the die.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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