It refers to a compound of formula I, where: R1 is 1H-pyrrole-2-yl, 1H-pyrrole-3-yl or 1H-pyrazol-3-yl； R2 is hydrogen, halogen, CN, among others； R3 and R4 are independently hydrogen or methyl, additionally refers to a compound Ib, where: R1 is 1H-pyrazol-3-yl, R2 is hydrogen, halogen, among others； R4 is hydrogen or methyl. Preferred compounds are: 4 - [(2- (morpholin-4-yl) -8- [2H-pyrazol-3-yl] - [1,7] -naphthyridin-4-yl] phenyl-N-ethoxycarbonyl-S- methylsulfoximide； 4 - [(2- (morpholin-4-yl) -8- [2H-pyrazol-3-yl] - [1,7] -naphthyridin-4-yl] phenyl-S-methylsulfoximide；There are others He also mentioned a combination of a composer and a pharmacist. These compounds of 2 - (morfolin-4-il) - 1,7-naftiridine can be used to treat extremely diffuse diseases.Se refiere a un compuesto de formula I, donde: R1 es 1H-pirrol-2-il, 1H-pirrol-3-il o 1H-pirazol-3-il； R2 es hidrogeno, halogeno, CN, entre otros； R3 y R4 son independientemente hidrogeno o metilo, adicionalmente se refiere a una compuesto Ib, donde: R1 es 1H-pirazol-3-il, R2 es hidrogeno, halogeno, entre otros； R4 es hidrogeno o metilo. Son compuestos preferidos: 4-[(2-(morfolin-4-il)-8-[2H-pirazol-3-il]-[1,7]-naftiridin-4-il]fenil-N-etoxicarbonil-S-metilsulfoximida； 4-[(2-(morfolin-4-il)-8-[2H-pirazol-3-il]-[1,7]-naftiridin-4-il]fenil-S-metilsulfoximida； entre otros. Tambien se refiere a una composicion y a una combinacion farmaceutica. Dichos compuestos derivados de 2-(morfolin-4-il)-1,7-naftiridina son utiles en el tratamiento de enfermedades hiperproliferativas
