Chugai Seiyaku Kabushiki Kaisha;Fukuoka University
发明人:
Yasunami, Yohichi
申请号：
AU2006300234
公开号：
AU2006300234B2
申请日:
2006.10.13
申请国别(地区):
AU
年份:
2013
代理人:
摘要：
An anti-IL-6 receptor antibody is examined on its inhibitory effect against transplanted islet dysfunction produced after islet transplantation. As a result, it is found that the anti-IL-6 receptor antibody can reduce the transplanted islet dysfunction, improve the survival of the transplanted islet, and also improve the hyperglycemic state of a recipient. It is also found that administration of the anti-IL-6 receptor antibody enables to prevent the production of an inflammatory cytokine in an infiltrating cell after the transplantation. Thus, it is now found that transplanted islet dysfunction produced after islet transplantation can be prevented by using the anti-IL-6 receptor antibody.
