Organ transplant rejection inhibitor containing anti-HMGB-1 antibody

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专利权人:

株式会社シノテスト;国立大学法人 鹿児島大学;学校法人福岡大学

发明人:

安波 洋一,丸山 征郎,山田 晋吾

申请号：

JP2008558147

公开号：

JP5285437B2

申请日:

2008.02.15

申请国别(地区):

JP

年份:

2013

代理人:

摘要：

An objective of the present invention is to provide effective methods for suppressing rejection in organ transplantation, in particular, pancreatic islet transplantation which is useful in treating diabetes. The present invention demonstrated that antibodies against HMGB-1 suppressed the rejection in pancreatic islet transplantation and promoted the survival of grafted pancreatic islets. Thus, the present invention provides agents that comprise an anti-HMGB-1 antibody for suppressing rejection in organ transplantation.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/