The invention is an interface device and system for establishing an operatinginterface between an injector device and diagnostic imaging equipment. In oneembodiment, the interface device may permit an operator to concurrentlyoperate and control the injector device and the imaging equipment. Theinterface device may permit the injector system and the imaging system tocommunicate information regarding their current and future operational statuswith each other. The interface device may be used to synchronize the operationof the imaging equipment and the injector device. In one embodiment, theinjector device and the imaging equipment may be able to communicate with eachother directly or through the interface device via a communications protocolcomprising binary logic signals. The binary logic signals may comprise one ormore of a low strength signal, a high strength signal, an oscillating signalthat oscillates between low and high signal strength, and combinations thereof.