The present Invention relates to Derivatives of morpholine (Uncle) have the formula (i) in donder1 is selected Alquinilo Ciano, (2 - (4c), alkyl, cycloalkyl 4c 1 - (3) - (4 - 6), cicloalquenilo 6c), bicicloalquilo (6 - 8c) bicyclic Group (8, 10), each replaced optionally with Lquilo (1 - 4c), phenyl, naphthyl, biphenyl,Each optionally substituted with one or more substituents are selected independently of halogen, alkyl (C1 - 4c) optionally substituted with one or more Atoms of Fluorine, alquinilo (2 - (4c), C1 - 4c) alkoxy optionally substituted with one or more Atoms of Fluorine, amino, Dialquilamino (C1 - 4c), SO2 (1 - 4C alkyl, alkyl (1) co - 4c), co or alkyl (1 - 4c)Co (NH 4C alkyl and cycloalkyl C1 - (3) - 6C) with benzyl, phenyl, phenoxy substituted Benzyloxy, feniletilo monocyclic heterocycle or, Optionally, each substituted with alkyl (1 - 4c), optionally substituted monocyclic heterocycle with (C1 - Halogen, alkyl or phenyl Sustituid 4c) Or optionally alkyl (1 - 4)Bicyclic heterocycle substituted alkyl optionally (C1 - 4c)； to select - CO - O -, - or - NH - CO, co, co - NH, - C = C -, - or - - CCh3 and the Liaison Group - and N - (CH2) - X - Where and is connected to R1 and Select a Link, - O -, - S -, - and - SO2 -, -, - and - CH2 -, co -, - or - CO, co or co -, - NH -, - NH - CO -- C = C and C? C； n is an integer from 1 to 10； and X is attached to the phenylene Group / piridilo and select a Link, - O -, - S, - So - SO2 -, -, - NH -, co -, - C = C and C? C； The structure of the B Ring optionally contains a nitrogen Atom； R2 is H, alkyl (C1 - 4c) optionally substituted with one or more Atoms of Fluorine,(C1 - 4c) alkoxy optionally substituted with one or more Atoms of Fluorine, or Halogen； yr3 is alquileno (1 - 4C - R5) where the Group can be substituted with alquileno (CH2) 2 to form a rest ciclopropilo or one or two Halogen ATOMS, or R3 is cicloalquileno (3 - 6C) - R5 or co - CH2 - R5, d Onde R5 is - Oh, - COOH, opo3h2 PO3H2,,- cooalquilo (C1 - 4c) or t
