PROBLEM TO BE SOLVED: To provide a composition for accelerating the penetration through the skin, which can dramatically improve the penetration of a medicine through the skin without requiring the shaping of the medicine in a particulate structure or the like and without causing damage to dermal tissues, and also provide a preparation for transdermal administration and a skin patch preparation, each of which contains the composition for accelerating the penetration through the skin.SOLUTION: A composition for accelerating the penetration through the skin contains a flavonoid compound and can be used for accelerating the penetration of a medicine through the skin.【課題】薬物を粒子構造に成形すること等を必要とせず、皮膚組織の破壊を伴わずに薬物の皮膚透過性を飛躍的に向上させることができる皮膚透過促進組成物を提供する。また、該皮膚透過促進組成物を含む経皮投与製剤及び貼付製剤を提供する。【解決手段】フラボノイド化合物を含み、薬物の皮膚透過を促進せしめるために用いられる皮膚透過促進組成物。【選択図】なし