SCHAAB, KEVIN,WHITLEY, PAUL E.,CHAVEZ, FLAVIO,IORGA, KAYLA R.
申请号:
CA2999302
公开号:
CA2999302A1
申请日:
2016.09.23
申请国别(地区):
CA
年份:
2017
代理人:
摘要:
The present invention relates to methods and novel intermediates useful in the preparation of a compound or a pharmaceutically acceptable salt thereof. An objective of the present invention is to provide methods of preparing bile acid derivatives and novel intermediates. A use of the methods and intermediates described relates to the synthesis of bile acid derivatives which activate both FXR and TGR5.