Schaab, Kevin,Whitley, Paul E.,Chavez, Flavio,Iorga, Kayla R.
申请号:
AU2016325619
公开号:
AU2016325619A1
申请日:
2016.09.23
申请国别(地区):
AU
年份:
2018
代理人:
摘要:
The present invention relates to methods and novel intermediates useful in the preparation of a compound or a pharmaceutically acceptable salt thereof. An objective of the present invention is to provide methods of preparing bile acid derivatives and novel intermediates. A use of the methods and intermediates described relates to the synthesis of bile acid derivatives which activate both FXR and TGR5.