A drilling control system (100). The drilling control system (100) comprises a drilling device (200) and a control unit (600) for controlling the drilling device (200). The drilling device (200) comprises a surgical tool (210), a drilling motor (240) capable of driving the surgical tool (210), a mechanical sensor (220) for sensing mechanical information, a manipulator assembly (230) for receiving an output control signal (640) and sensing spindle information (626), and a console (300) for mounting the manipulator assembly (230). The control unit (600) is connected to a spatial sensing system (400). The control unit (600) has biomechanical information (610) stored therein, and generates drilling information (620) according to the mechanical information (622) generated by the mechanical sensor (220), spatial information (624) generated by the spatial sensing system (400), and the spindle information (626). The control unit (600) further calculates and obtains a deviation index (630) according to the biomechanical information (610) and the drilling information (620), and sends the output control signal (640) to the drilling device (200) according to the deviation index (630). The drilling control system (100) improves the safety and precision of drilling. Further provided is a drilling control method.Linvention concerne un système de commande de forage (100). Le système de commande de forage (100) comprend un dispositif de forage (200) et une unité de commande (600) pour commander le dispositif de forage (200). Le dispositif de forage (200) comprend un outil chirurgical (210), un moteur de forage (240) capable dentraîner loutil chirurgical (210), un capteur mécanique (220) pour détecter des informations mécaniques, un ensemble manipulateur (230) pour recevoir un signal de commande de sortie (640) et détecter des informations relatives au mandrin (626), et une console (300) pour le montage de lensemble manipulateur (230). Lunité de commande (600) est raccordée à un syst