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COMPOSITIONS AND METHODS OF USE FOR AUGMENTED IMMUNE RESPONSE AND CANCER THERAPY
专利权人:
Glenn DRANOFF;Fei WANG;Jennifer BROGDON;Daniela CIPOLLETTA;Deborah A. KNEE
发明人:
Jennifer BROGDON,Daniela CIPOLLETTA,Glenn DRANOFF,Deborah A. KNEE,Fei WANG
申请号:
US15517872
公开号:
US20170306038A1
申请日:
2015.10.08
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The present invention provides antibody compositions, including, e.g., antibodies, engineered antibodies and antibody fragments that bind to a tumor necrosis factor receptor superfamily member (i.e., 18), and compositions comprising one or more additional therapeutic agents. Provided compositions are useful in enhancing CD4+ and CD8+ T cell responses, and in the treatment, amelioration and prevention of diseases that can be counteracted with an augmented immune response, e.g., cancers. Also provided are methods of use of combinations that find use in treatment or prevention of cancerous or infectious conditions and disorders.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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