MUSC Foundation for Research Development;National Jewish Health;The Regents of the University of Colorado, a body corporate
发明人:
V. Michael HOLERS,Joshua M. Thurman,Christian Taube,Erwin W. Gelfand,Gary Steven Gilkeson
申请号：
US14183213
公开号：
US20140154307A1
申请日:
2014.02.18
申请国别(地区):
US
年份:
2014
代理人:
摘要：
Disclosed are novel inhibitors of the alternative complement pathway and particularly, novel anti-factor B antibodies. Also disclosed is the use of such inhibitors to reduce or prevent airway hyperresponsiveness and/or airway inflammation by selectively inhibiting the alternative complement pathway, thereby treating diseases in which such conditions play a role. Also disclosed is the use of such inhibitors to reduce or prevent other diseases and conditions, including ischemia-reperfusion injury, by inhibition of the alternative complement pathway.
