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HUMAN MONOCLONAL ANTIBODIES TO PROTEIN TYROSINE KINASE 7 (PTK7) AND METHODS FOR USING ANTI-PTK7 ANTIBODIES
专利权人:
Li-Sheng LU;Chin PAN;Jonathan Alexander TERRETT
发明人:
Jonathan Alexander TERRETT,Li-Sheng LU,Chin PAN
申请号:
US13468624
公开号:
US20120219557A1
申请日:
2012.05.10
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention provides isolated monoclonal antibodies, particularly human monoclonal antibodies, that specifically bind to PTK7 with high affinity. Nucleic acid molecules encoding the antibodies of the invention, expression vectors, host cells and methods for expressing the antibodies of the invention are also provided. Immunoconjugates, bispecific molecules and pharmaceutical compositions comprising the antibodies of the invention are also provided. The invention also provides methods for detecting PTK7, as well as methods for treating various diseases, including cancer and infectious diseases, using anti-PTK7 antibodies.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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