Disclosed herein a pharmaceutical composition comprising aprepitant or a pharmaceutically acceptable salt thereof at least one hydrocarbon derivative selected from among a fatty acid of 14 to 18 carbon atoms and a fatty alcohol of 14 to 18 carbon atoms and at least one selected from among polyoxyethyelene type nonionic surfactant sucrose fatty acid ester and Macrogol 15 hydroxystearate. The pharmaceutical composition of the present disclosure can release aprepitant or a pharmaceutically acceptable salt thereof to effectively exert the pharmaceutical efficacy and can be dissolved in a fasted state simulated gastrointestinal fluid so that it can be useful for study on the in vivo pharmacokinetic behavior of aprepitant.
