PROBLEM TO BE SOLVED: To provide a pharmaceutical preparation for inhibiting the atrophy of an alimentary canal and kidney during weight reduction, and to provide a pharmaceutical composition and a food that contain the pharmaceutical preparation.SOLUTION: An oral composition is provided that contains branched chain amino acid by 1.5-2.5 g and has a combination of specific amounts of leucine, isoleucine and valine as the branched chain amino acid. In particular, the composition has a granular form and contains 10-80 wt.% of branched chain amino acid containing leucine, isoleucine, and valine. The oral composition is used under the conditions of weight reduction, food restriction, and nutrition intake restriction.COPYRIGHT: (C)2013,JPO&INPIT【課題】減量時に消化管及び腎臓の萎縮を抑制する製剤、該製剤を含有する医薬組成物及び食品の提供。【解決手段】分岐鎖アミノ酸を1.5~2.5g含有し、且つ、該分岐鎖アミノ酸としてのロイシン、イソロイシン及びバリンを、それぞれ特定量ずつ組み合わせて含有する、経口用組成物。特に、顆粒形態を有し、ロイシン、イソロイシン及びバリンからなる分岐鎖アミノ酸を10~80重量%含有する組成物。減量下、食事制限下、栄養摂取制限下における前記経口用組成物の使用。【選択図】なし