OHIO STATE INNOVATION FOUNDATION;RESEARCH INSTITUTE AT NATIONWIDE CHILDREN'S HOSPITAL
发明人:
Arthur Burghes,Paul Porensky,Brian Kaspar
申请号:
US14363670
公开号:
US09725716B2
申请日:
2012.12.06
申请国别(地区):
US
年份:
2017
代理人:
摘要:
Disclosed are compositions comprising an antisense oligonucleotide and a non-ionic, low-osmolar contrast agent. Also disclosed are methods of delivering an antisense oligonucleotide to a target sire comprising incorporating the antisense oligonucleotide into a composition comprising a non-ionic, low-osmolar contrast agent. Also disclosed are methods of treating a neurodegenerative disease comprising administering one or more of the compositions disclosed herein.