Pharmaceutical formula of fusion protein stabilizer TNFR：FC

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专利权人:

Sandoz AG

发明人:

DEUTEL, Britta,LAUBER, Thomas,FUERTINGER, Sabine

申请号：

ES12715107

公开号：

ES2759931T3

申请日:

2012.04.19

申请国别(地区):

ES

年份:

2020

代理人:

摘要：

The present invention relates to stable pharmaceutical liquid formulations of the fusion protein TNFR:Fc comprising different buffer systems and stabilizers. In particular, it could be demonstrated that the physical stability of TNFR:Fc is significantly improved by using a citrate buffer system and lysine as stabilizer.

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