Omid C. Farokhzad,Carolina Salvador-Morales,Weiwei Gao,Liangfang Zhang,Juliana M. Chan,Robert S. Langer
申请号:
US15097676
公开号:
US09649391B2
申请日:
2016.04.13
申请国别(地区):
US
年份:
2017
代理人:
摘要:
This disclosure relates to particles (e.g., nanoparticles and microparticles) that display multiple functionalized surface domains in a controlled mosaic pattern. The disclosure also provides simple methods to create various particles that have multiple functionalized surface domains while allowing the use of a wide variety of diverse core structures. The multiple functionalized domains provide controllable particle binding and orientation, and controlled and sustained drug release profiles.