Method for predicting a therapy response in subjects with multiple sclerosis

• 收藏
• 分享

专利权人:

The Cleveland Clinic Foundation

发明人:

Rudick, Richard A.,Ransohoff, Richard M.

申请号：

AU2011268223

公开号：

AU2011268223A1

申请日:

2011.06.17

申请国别(地区):

AU

年份:

2013

代理人:

摘要：

A method is provided for determining the efficacy of interferon -beta (IFN-β) therapy in a subject with multiple sclerosis. One step of the method can include obtaining a biological sample from the subject. After obtaining the biological sample, the expression level of at least one interferon-regulated gene (IRG) and/or variant thereof can be determined. Increased or decreased expression of the at least one IRG and/or variant thereof as compared to a control may indicate that the subject will respond poorly to IFN-β therapy.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/