Beth Israel Deaconess Medical Center, Inc.;Triad National Security, LLC
发明人:
Dan H. BAROUCH,Bette T. KORBER,William M. FISCHER
申请号:
US16441703
公开号:
US20190314492A1
申请日:
2019.06.14
申请国别(地区):
US
年份:
2019
代理人:
摘要:
The invention provides compositions, methods, and kits for the treatment or prevention of viral infections. The polyvalent (e.g., 2-valent) vaccines described herein incorporate computationally-optimized viral polypeptides that can increase the diversity or breadth and depth of cellular immune response in vaccinated subjects.