According to the present invention, an immunoisolation membrane including a porous membrane is provided at least at a part of a boundary between the inside and the outside, the porous membrane contains a polymer, and a layered dense portion having a minimum pore size is provided in the membrane. The pore diameter continuously increases in the thickness direction from the dense portion toward both the surface A and the surface B of the porous film, and the porosity near the surface B is 65%. That is, the average pore size of the surface B is larger than the average pore size of the surface A, the surface B is disposed on the inner side, the surfaces B face each other, and the porous membranes bond to each other. Provided is an implanting chamber having a portion, and an implanting device in which a biological constituent is contained in the implanting chamber. In the transplantation chamber of the present invention, the decrease in substance permeability is unlikely to occur, and the strength of the joint between the immunoisolation membranes is high.本発明により、内部と外部との境界の少なくとも一部に多孔質膜を含む免疫隔離膜を有し、上記多孔質膜がポリマーを含み、かつ孔径が最小となる層状の緻密部位を膜内に有し、上記緻密部位から上記多孔質膜の一方の表面Ａおよび他方の表面Ｂの双方に向かって厚み方向で孔径が連続的に増加しており、上記表面Ｂ付近の空孔率は６５％以上であり、上記表面Ｂの平均孔径は上記表面Ａの平均孔径より大きく、上記表面Ｂは上記内部側に配置され、上記表面Ｂ同士が対向して上記多孔質膜同士が接合している接合部を有する移植用チャンバー、ならびに上記移植用チャンバーに生物学的構成物が内包されている移植用デバイスが提供される。本発明の移植用チャンバーは、物質透過性の低下が生じにくく、免疫隔離膜同士の接合部の強度が高い。
