An endoscopic diagnosis system includes first and second narrowband light sources for emitting respectively first and second narrowband lights having a wavelength range different from each other, a first image sensor for receiving reflected light of the first narrowband light illuminating a subject to acquire a narrowband light image in a narrowband light observation mode, a second image sensor for receiving first autofluorescence emitted from the subject as the first narrowband light illuminates the subject to acquire a first autofluorescence image in a first autofluorescence observation mode and receiving second autofluorescence emitted from the subject as the second narrowband light illuminates the subject to acquire a second autofluorescence image in a second autofluorescence observation mode, and a light source controller for increasing emission amounts of the first and the second narrowband light in the first and the second autofluorescence observation mode.
