An endoscopic diagnosis system comprises a first narrowband light source for emitting first narrowband light having a given wavelength range, a second narrowband light source for emitting second narrowband light having a wavelength range different from that of the first narrowband light, a first image sensor for receiving reflected light of the first narrowband light illuminating a subject from the subject to acquire a narrowband light image in a narrowband light observation mode, a second image sensor for receiving first autofluorescence emitted from the subject as the first narrowband light illuminates the subject to acquire a first autofluorescence image in a first autofluorescence observation mode and receiving second autofluorescence emitted from the subject as the second narrowband light illuminates the subject to acquire a second autofluorescence image in a second autofluorescence observation mode, and a light source controller for increasing emission amounts of the first and the second narrowband light in the first and the second autofluorescence observation mode to emission amounts greater than emission amounts used in the narrowband light observation mode.
