BINDERUP, ERNST TORNDAL,HJARNAA, PERNILLE-JULIA VIG
申请号：
CA2426601
公开号：
CA2426601C
申请日:
2001.11.14
申请国别(地区):
CA
年份:
2015
代理人:
摘要：
The invention relates to compounds of formula (I), wherein X1 and X2independently represent a bond； a straight, branched and/or cyclic hydrocarbondiradical, optionally substituted with one or more hydroxy, halogen, nitro,amino, cyano, aminosulfonyl, alkylsulfonylamino, alkylcarbonyl, formyl,aminocarbonyl or alkylcarbonylamino； a heteroarylene or non-aromaticheterocyclic hydrocarbon diradical, all of which are optionally substitutedwith one or more straight, branched and/or cyclic non-aromatic hycrocarbonradical, hydroxyl, halogen, amino, nitro, cyano, aminosulfonyl,alkylsulfonylamino, alkylcarbonyl, formyl, aminocarbonyl oralkylcarbonylamino； Y1 and Y2 independently represent a bond, an etherdiradical (R'-O-R''), an amine diradical (R'-N-R''), O, S, S(O), S(O)2, C(O),NH-CO, CO-NH, SO2-N(R'), methylene or N(R')-SO2 wherein R' et R''independently represent straight or branched hydrocarbon diradicals containingup to 4 carbon atoms； Y3 represents O, O-C(O), C(O)-O, N(R8), R8 beinghydrogen or C1-4alkyl； R1 represents hydrogen or straight, branched and/orcyclic alkyl, optionally substituted with phenyl； or an aromatic hydrocarbonradical； R2 represents aryl, heteroaryl or a non-aromatic heterocyclichydrocarbon radical, all of which are optionally substituted；tetrahydropyranyloxy, di-(C1-4 alkoxy)phosphinoyloxy or C1-4alkoxycarbonylamino； R3 represents hydrogen； a straight, branched and/orcyclic hydrocarbon radical, optionally substituted with one or more amino,hydroxy, carboxy, halogen, nitro, cyano, alcoxy, aminocarbonyl, C1-4alkoxycarbonyl, C1-4alkoxycarbonylamino, sulfo, hydroxysulfonyloxy,dihydroxyphosphinoyloxy, phosphono, sulfamino, aminosulfonyl, aminoacylaminoor dialkoxyphosphinoyl； heteroaryl or a non-aromatic heterocyclic hydrocarbonradical, all of which are optionally substituted with one or more straight,branched and/or cyclic hydrocarbon radical, amino, hydroxy, carboxy, halogen,nitro, cyano, alkoxy,
