您的位置: 首页 > 农业专利 > 详情页

Compounds 4 - amino - imidazoquinolina
专利权人:
F. HOFFMANN-LA ROCHE AG
发明人:
申请号:
ARP150101179
公开号:
AR100137A1
申请日:
2015.04.20
申请国别(地区):
AR
年份:
2016
代理人:
摘要:
The present application relates to 4-amino-imidazoquinoline compounds and pharmaceutically acceptable salts thereof. These compounds are RTT agonists and, therefore, may be useful as medicaments for the treatment of diseases such as cancer or infectious diseases. Claim 1: Compound of formula (1) wherein: R¹ is C₁₋₇ alkyl or C₁₋₇ alkoxy-C₁₋₇ alkyl;R² is selected from the group consisting of hydrogen, halogen, C₁₋₇ hydroxyalkyl,C₁₋₇ alkoxy-alkyl,carboxyl, carboxy-C₁₋₇ alkyl,Cbox carboxy-alkenyl,aminocarbonyl-C₁₋₇ alkyl,C₂₋₇ aminocarbonyl-alkenyl,C₁₋₇-carbonyl-C₁₋₇ alkyl alkylamino,1. Lease c83218c83331-83278carbon-alquenilo c832283331-8327;C₁₋₇ alkoxycarbonyl-C₁₋₇ alkyl,C₁₋₇-Cque alkenyl alkoxycarbonyl,C₁₋₇-sulfonyl-C₁₋₇ alkyl,1. Sulfuric acid-c833218d83277a;C₁₋₇-sulfamoyl-C₁₋₇ alkyl,phenyl, said phenyl being unsubstituted or substituted with one, two or three groups selected from the group consisting of C₁₋₇ alkyl,C₁₋₇ cycloalkyl,Halogen, halogen tar c8332127a,a. Halogens alcoxi c8321c83318327;1. Hidroxi, hydroxi hydrocarbon c8332127a;C₁₋₇ alkoxy,ciano carboxilo alcoxicarbonilo CC₁₋₇ alkoxycarbonyl-C₁₋₇ alkyl,C₁₋₇ alkylsulfonyl,C₁₋₇ hydroxy-alkylsulfonyl,C₁₋₇-C alkylsulfonyl alkoxy,Cbox-carboxy-alkyl sulfonylC₁₋₇ alkoxycarbonyl-C₁₋₇ alkylsulfonyl,amino, C₁₋₇ alkylamino,di-Cila alkylamino and nitro, and phenoxy, said phenoxy being unsubstituted or substituted with one, two or three groups selected from the group consisting of C₁₋₇ alkyl,C₁₋₇ cycloalkyl,Halogen, halogen tar c8332127a,a. Halogens alcoxi c8321c83318327;1. Hidroxi, hydroxi hydrocarbon c8332127a;C₁₋₇ alkoxy,ciano carboxilo alcoxicarbonilo CC₁₋₇ alkoxycarbonyl-C₁₋₇ alkyl,C₁₋₇ alkylsulfonyl,C₁₋₇ hydroxy-alkylsulfonyl,C₁₋₇-C alkylsulfonyl alkoxy,Cbox-carboxy-alkyl sulfonylC₁₋₇ alkoxycarbonyl-C₁₋₇ alkylsulfonyl,amino, C₁₋₇ alkylamino,Di lease c8327a and nitrogen; R3 is hydrogen or halogen; r83088 is selected from the following groups: O - (ch83222244) - nhr8309;y -O- (CO) - (CH) -NHRwherein: m is selected from
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
相关发明人
相关专利

意 见 箱

匿名:登录

个人用户登录

找回密码

第三方账号登录

忘记密码

个人用户注册

必须为有效邮箱
6~16位数字与字母组合
6~16位数字与字母组合
请输入正确的手机号码

信息补充