Binoy K. Bordoloi,Joseph Zavatsky,Chetan Anirudh Khatri,Olajompo Moloye-Olabisi
申请号:
US13107375
公开号:
US20120288530A1
申请日:
2011.05.13
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention is directed in one embodiment to a tissue adhesive or sealant composition comprising an electrophilic group containing cross-linking compound having a linker moiety of a diglycolic acid, a water soluble core moiety and an electrophilic group that is covalently bonded to the diglycolic acid linker moiety and a nucleophilic group containing protein. In other embodiments, the present invention is directed to a delivery device or a medical device on which the composition has been applied or incorporated therein. The present invention is also directed to a method for sealing tissue using the tissue adhesive or sealant composition.