Emory University;Georgia Tech Research Corporation;Chapman University;Children's Healthcare of Atlanta, Inc.
发明人:
Wilbur A. Lam,Caroline Hansen,Yumiko Sakurai,Andrew Lyon
申请号：
US16074643
公开号：
US20200306199A1
申请日:
2017.01.31
申请国别(地区):
US
年份:
2020
代理人:
摘要：
This disclosure relates to microcapsule particles for targeted delivery of drugs. In certain embodiments, the particles comprise polyelectrolyte polymers, e.g., layers of anionic polymers and cationic polymers. In certain embodiments, the particles have a fibrinogen coating. In certain embodiments, the particles contain a polysaccharide core and/or a polysaccharide coating encapsulating drugs, proteins, clotting agents, coagulation factors, or anticoagulants. In certain embodiments, this disclosure contemplates methods of using particles disclosed herein to prevent or reduce onset of or duration of bleeding. In certain embodiments, this disclosure contemplates methods of using particles disclosed herein to prevent or reduce onset of blood clotting.
