PROBLEM TO BE SOLVED: To provide a solid state composition produced by a simple method and preventing irritation to digestive tracts caused by a medicine having the digestive tract-irritating property.SOLUTION: This solid state composition comprises a digestive tract-irritating medicine and a water swellable polymer, and is prepared by a wet granulation process by using water or a water-containing alcohol.COPYRIGHT: (C)2008,JPO&INPIT【課題】簡易な製造方法で製造できる消化管刺激性を有する薬物による消化管への刺激を防止した固形組成物の提供。【解決手段】消化管刺激性薬物および水膨潤性高分子を含有し、水又は含水アルコールで湿式造粒して得られる経口固形組成物。【選択図】なし
