LIN, SHWU BIN,林淑萍,林淑萍,CHANG, CHAO LIN,张肇麟,張肇麟,CHEN, TENG HAI,陈登海,陳登海
申请号：
TW102104538
公开号：
TW201431855A
申请日:
2013.02.06
申请国别(地区):
TW
年份:
2014
代理人:
摘要：
Disclosed herein is a novel use of Colossolactone(s) isolated from Ganoderma colossum (Fr.) Baker, as an adjuvant of anti-cancer agents. The in vitro studies confirmed that it may effectively enhance the growth inhibitory effect of the anti-cancer agents on cancerous cells, especially cell toxicity effect of Gefitinib towards non-small cell lung cancerous cells, or Sorafenib towards hepatocellular carcinoma cells.在此揭示一種自黃芝(Ganoderma colossum(Fr.)Baker)中分離出來之羊毛固醇三萜類化合物作為抗癌藥物佐劑的新穎用途,離體試驗證實其具有可增強抗癌藥物殺死癌細胞的功效,特別是可增強抗癌藥物對於已對艾瑞莎具有抗性的非小細胞肺癌細胞或對蕾沙瓦具有抗性的肝癌細胞產生細胞毒性的效果。
