您的位置: 首页 > 农业专利 > 详情页

FIVE-MEMBERED HETEROCYCLIC PYRIDINE COMPOUNDS AND PREPARATION METHOD AND USE THEREOF
专利权人:
SHANKHAJ INSTITYUT OF MATIRIA MEDIKA; CHAJNIZ EKEDIMI OF SAJNSES
发明人:
SHEN Tszinkan (CN),ШЭНЬ Цзинкан (CN),GEN Mejyuj (CN),ГЭН Мэйюй (CN),DIN Tszyan (CN),ДИН Цзянь (CN),SYU Bin (CN),СЮ Бин (CN),AJ Tszin (CN),АЙ Цзин (CN),MA Yujchi (CN),МА Юйчи (CN),VAN Syu (CN),ВАН Сю (,ВАН Сю (CN),VAN Syu (
申请号:
RU2016101983
公开号:
RU0002668074C2
申请日:
2014.06.18
申请国别(地区):
RU
年份:
2018
代理人:
摘要:
FIELD: chemistry.SUBSTANCE: invention relates to the field of organic chemistry, namely a heterocyclic compound of formula (X) and a pharmaceutically acceptable salt thereof, where X, Y and Z, each separately constitute N or C and at least two of them - X, Y or Z – are represent N, and when X represents N, Z represents N; represents a simple or a double bond; W and V are selected from H or unsubstituted C1-C4 alkyl; R1 represents a substituted with 1-2 substituents or unsubstituted mono- or bicyclic C6-C10 aryl; substituted with 1 or 2 substituents or unsubstituted mono- or bicyclic 5-9 membered heteroaryl containing 2-3 heteroatoms selected from N, O and S; wherein the substituent is halogen, nitro, cyano, hydroxyl; unsubstituted or trihaloid substituted C1-C6 alkyl, C1-C6 alkoxy, C1-C6 alkylcarbonyl, -NRaRb, -OC(O)-Rf, unsubstituted phenyl or phenyl substituted with 1-3 R3, or unsubstituted monocyclic 5-6 membered heteroaryl, containing 1 to 2 heteroatoms selected from N and S, or a 5-6 membered heteroaryl containing 1 to 2 heteroatoms, selected from N, substituted by 1 R4; R2 represents C1-C4 alkoxycarbonyl; -NRcRd; substituted with 1-3 substituents or unsubstituted mono- or bicyclic C6-C10 aryl; substituted with 1 substituent or unsubstituted mono- or bicyclic 5-10 membered heteroaryl containing 1 to 2 heteroatoms selected from N, O and S; or substituted by 1 substituent or unsubstituted monocyclic partially unsaturated 6-membered heterocyclyl containing 1 heteroatom selected from N; wherein the substituent is halogen, C2 alkylenedioxy, unsubstituted or trihaloid- or NRcRd-substituted C1-C6 alkyl either C3-C6 cycloalkyl, C1-C6 alkoxy, C1-C6 sulfamide, -NRaRb, -C(O)R', morpholinyl or unsubstituted or substituted R" piperidinyl, wherein R3 is a halogen, cyano, C1-C2 alkylenedioxy, unsubstituted or trihaloid- or morpholinyl substituted C1-C6 alkyl, C1-C6 alkoxy, -NRaRb, -C(O)R' or morpholinyl; R4 represents halogen, unsubstituted C1-C6 alkyl either unsubstituted o
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

意 见 箱

匿名:登录

个人用户登录

找回密码

第三方账号登录

忘记密码

个人用户注册

必须为有效邮箱
6~16位数字与字母组合
6~16位数字与字母组合
请输入正确的手机号码

信息补充