The present invention relates to the use of (R)-3-[1-(2,6-Dichloro-3-fluoro-phenyl)-ethoxy]-5-(1- piperidin-4-yl-1H-pyrazol-4-yl)-pyridin-2-ylamine,a novel c-Met/HGFR inhibitor, for treating abnormal cell growth in mammals.In particular, the invention provides methods of treating mammals sufferingfrom cancer.