Refers to compounds (a) and (b) or the pharmaceutically acceptable salts thereof, wherein (a) is (2S,4S) - 1 - [(3 - Chloro - fluoro - 2 - phenyl) methyl] - 4 - [[3 - [(4-fluoro-6 - 5 - methyl - 1H pyrazole IL - 3 - 2 - pyridyl) methyl] methyl] - 2 - (piperidin-4-yl carboxylic acid and (b) (2R,1 - [(4R) - 2, 3 - Chloro - fluoro phenyl) methyl] - 4 - [[3 - [(4-fluoro-6 - 5 - methyl - 3 - 1H pyrazole - il) 2 - pyridyl) methyl] - 2 - methyl - 4 - carboxylic piperidin. It also relates to a composition.These compounds are inhibitors of the Enzyme kinase Aurora to be useful in the treatment of Head and Neck CancerSe refiere a compuestos (a) y (b) o sales farmaceuticamente aceptables de los mismos, donde (a) es (2S,4S)-1-[(3-cloro-2-fluoro-fenil)metil]-4-[[3-fluoro-6-[(5-metil-1H-pirazol-3-il)2-piridil]metil]-2-metil-piperidin-4-carboxilico y (b) es (2R,4R)-1-[(3-cloro-2-fluoro-fenil)metil]-4-[[3-fluoro-6-[(5-metil-1H-pirazol-3-il)2-piridil]metil]-2-metil-piperidin-4-carboxilico. Tambien se refiere a una composicion. Dichos compuestos son inhibidores de la enzima cinasa Aurora A siendo utiles en el tratamiento de cancer de cabeza y cuello
