THE PROVOST, FELLOWS, FOUNDATION SCHOLARS, & THE OTHER MEMBERS OF BOARD, OF THE COLLEGE OF THE HOLY& UNDIV. TRINITY OF QUEEN ELIZABETH NEAR DUBLIN;THE COOMBE LYING-IN HOSPITAL
发明人:
申请号:
EP09783381.8
公开号:
EP2334300B1
申请日:
2009.09.24
申请国别(地区):
EP
年份:
2016
代理人:
摘要:
The invention provides a method for treating or preventing preterm labor in pregnant female subjects. The method comprises the step of administering a therapeutically effective amount of a Toll-like Receptor 9 antagonist sufficient to prevent the activation of Toll-like Receptor 9 by fetal DNA. The invention further provides compositions comprising a Toll-like Receptor 9 antagonist for use in the methods of the invention. The compositions and methods of the present invention enhance gestation and therefore improve neonatal morbidity and mortality.