Luke Anthony O'Neill;Sean Daly;Luke Anthony ONeill;John O'Leary;Andrea Scharfe Nugent
发明人:
Luke Anthony O'Neill,John O'Leary,Sean Daly,Andrea Scharfe Nugent,Luke Anthony ONeill,John OLeary
申请号：
US13120605
公开号：
US08933011B2
申请日:
2009.09.24
申请国别(地区):
US
年份:
2015
代理人:
摘要：
The invention provides a method for treating or preventing preterm labor in pregnant female subjects. The method comprises the step of administering a therapeutically effective amount of a Toll-like Receptor 9 antagonist sufficient to prevent the activation of Toll-like Receptor 9 by fetal DNA. The invention further provides compositions comprising a Toll-like Receptor 9 antagonist for use in the methods of the invention. The compositions and methods of the present invention enhance gestation and therefore improve neonatal morbidity and mortality.
