VARIANTES DE QUEUE DE THERAPEUTIQUES REDOX-ACTIVES DESTINEES AU TRAITEMENT DE MALADIES MITOCHONDRIALES ET D'AUTRES ETATS ET A LA MODULATION DE BIOMARQUEURS ENERGETIQUES

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专利权人:

INC.;EDISON PHARMACEUTICALS

发明人:

MILLER, GUY M.,HECHT, SIDNEY M.

申请号：

CA2622523

公开号：

CA2622523C

申请日:

2006.09.15

申请国别(地区):

CA

年份:

2014

代理人:

摘要：

Methods of treating or suppressing mitochondrial diseases, such asFriedreich'sataxia (FRDA), Leber's Hereditary Optic Neuropathy (LHON), mitochondrialmyopathy,encephalopathy, lactacidosis, stroke (MELAS), or Kearns-Sayre Syndrome (KSS)aredisclosed, as well as compounds useful in the methods of the invention. Energybiomarkers useful in assessing the metabolic state of a subject and theefficacy oftreatment are also disclosed. Examples of compounds of the invention includecompoundsof formula:(see formula I)or(see formula I-red) .

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/