The present invention relates to a composition for preventing the hair loss or promoting the hair growth, and according to the present invention, Wnt protein-derived peptides, polydeoxyribonucleotides or mixtures thereof increase the secretion of β-catenin, and increase the growth of keratinocytes, fibroblasts and dermal papilla cells which are hair constituent cells, by the cell activation and activation of signal transduction pathway for promoting the hair growth signaling system and to prevent the hair loss and promote the hair growth and therefore, Wnt protein-derived peptides, polydeoxyribonucleotides or mixtures thereof having the above effect can be used as a cosmetic composition, a pharmaceutical composition or a health food composition for preventing the hair loss or promoting the hair growth.
