INDUSTRY-ACADEMIC COOPERATION FOUNDATION; YONSEI UNIVERSITY
发明人:
PARK, TAE SUN,박태선
申请号：
KR1020120074407
公开号：
KR1012694900000B1
申请日:
2012.07.09
申请国别(地区):
KR
年份:
2013
代理人:
摘要：
PURPOSE: A composition for prevention or treatment of hair loss containing secoiridoid glucoside derivative as an active ingredient is provided to show an excellent effect on human hair or wool by taking a natural compound as an active ingredient which has no side effects. CONSTITUTION: A pharmaceutical composition for accelerating hair growth contains secoiridoid glucoside derivative represented by chemical formula 2, or its hydrolysate as an active ingredient. The composition increases an expression of IGF-1(Insulin-like growth factor 1), VEGF(vascular endothelial growth factor), HGF(hepatocyte growth factor), KGF(keratocyte growth facfor) or &beta；-catenin. A functional food composition for improving hair growth contains secoiridoid glucoside derivative represented by chemical formula 2, or its hydrolysate as an active ingredient. A pharmaceutical composition for accelerating hair growth does not have side by taking a natural compound as an active ingredient.본 발명은 세코이리도이드 글루코사이드(secoiridoid glucoside) 유도체 또는 이의 가수분해 산물을 유효성분으로 포함하는 탈모의 예방 또는 치료용 약제학적 조성물, 탈모 개선 또는 발모 촉진용 화장료 조성물 및 기능성 식품 조성물에 을 제공한다.본 발명의 조성물은 만성질환인 탈모에 있어서 장기 투여시에도 부작용이 없는 천연 화합물을 유효성분으로 하고 있을 뿐만 아니라, 육모 및 양모에 뛰어나고 안정적인 효능을 보여 효율적인 탈모 치료제 또는 발모 촉진용 화장료/기능성 식품 조성물로 유용하게 이용될 수 있다.
